Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex
نویسندگان
چکیده
منابع مشابه
Conjunctive representation of position, direction, and velocity in entorhinal cortex.
Grid cells in the medial entorhinal cortex (MEC) are part of an environment-independent spatial coordinate system. To determine how information about location, direction, and distance is integrated in the grid-cell network, we recorded from each principal cell layer of MEC in rats that explored two-dimensional environments. Whereas layer II was predominated by grid cells, grid cells colocalized...
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As the interface between hippocampus and neocortex, the entorhinal cortex is likely to play a pivotal role in memory. To determine how information is represented in this area, we measured spatial modulation of neural activity in layers of medial entorhinal cortex projecting to the hippocampus. Close to the postrhinal-entorhinal border, entorhinal neurons had stable and discrete multipeaked plac...
متن کاملThe Preferred Directions of Conjunctive Grid X Head Direction Cells in the Medial Entorhinal Cortex Are Periodically Organized.
The discovery of speed-modulated grid, head direction, and conjunctive grid x head direction cells in the medial entorhinal cortex has led to the hypothesis that path integration, the updating of one's spatial representation based on movement, may be carried out within this region. This hypothesis has been formalized by many computational models, including a class known as attractor network mod...
متن کاملTopography of Head Direction Cells in Medial Entorhinal Cortex
BACKGROUND Neural circuits in the medial entorhinal cortex (MEC) support translation of the external environment to an internal map of space, with grid and head direction neurons providing metrics for distance and orientation. RESULTS We show here that head direction cells in MEC are organized topographically. Head direction tuning varies widely across the entire dorsoventral MEC axis, but in...
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Finding our way in spatial environments is an essential part of daily life. How do we come to possess this sense of direction? Extensive research points to the hippocampus and entorhinal cortex (EC) as key neural structures underlying spatial navigation. To better understand this system, we examined recordings of single-neuron activity from neurosurgical patients playing a virtual-navigation vi...
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ژورنال
عنوان ژورنال: Science
سال: 2006
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1125572